Using Pragmatic Decentralized Recruitment Strategies in Practice Based Research: The PREVENTABLE Study

Context: COVID-19 has severely impacted traditional approaches to Practice Based Research recruitment strategies. The Center for Primary Care at Atrium Health is actively enrolling participants as a site PRagmatic EValuation of evENTs And Benefits Lipid-lowering in oldEr adults (PREVENTABLE), multi-center, decentralized trial. Objective: Pragmatic, trials are an effective way reach individuals hesitant come in-clinic well reducing study costs. Study Design and Analysis: REDCap used review sign informed e-consents. PREVENTABLE website allows sites directly enter data. central pharmacy mails 90-day supply drug participants. A call center staffed with personnel trained on protocol, which includes phone screen cognitive function (TICS-M), performs follow up. Settings or Dataset: across 86 US based sites, including Veteran Affairs. We recruiting from 77 primary care research practices nearly 3,000 square miles. Participants offered options consenting completing related activities clinic via video capable device. Population Studied: aged ≥75 years without dementia, disability, clinically evident cardiovascular disease. Intervention/Instrument: number who e-consent compared those do not. Outcome Measures: e-consents obtained tracked through REDCap, while the length virtual consents person Atrium’s healthcare software. Results: Currently, 12 53 e-consented, rest consented in-person. 5 patients were interested but did not participate due limited internet transportation access. Study order activity completed between include more than 55 shipped delivered orders. check-in out times software, visits take ~1.25 hours 1 on-site ~2 up 3 personnel. Conclusion: design allowed recruit, enroll, retain living 40+ miles away alternate addresses. time effort saved by